Efficiency of russian white chickens selection as a way to increase vaccine raw material output

Nowadays in Russia there is rather hard epizootic situation in animal husbandry. This is connected on the one hand with high concentration of herds and flocks and violation of sanitary rules, on the other hand with import of breeding materials from abroad. The only efficient way of disease prevention is development and production of specialized vaccines. Growth of the vaccines’ market and volumes of production stimulated demand in raw materials and need in development of efficient methods of viral raw materials production. A big part of vaccines is being produced on the base of live chicken embryos. But currently in Russia there not available own specialized chicken populations, bred for production of SPF eggs (substrate for live vaccines production) and for production of so called “clean vaccines” (for production of inactivated vaccines). The reason: to get an SPF-egg there is needed a special technology of keeping and feeding, which excludes contamination by various viral or bacterial agents; at the same time there is not used any vaccinations. During production of “clean eggs” there is possible a mild vaccination program or full absence of vaccinations against some definite diseases. For the first time the authors have offered a new selection method, which enables to breed specialized chicken populations with increased content of allantoic-amniotic liquids in eggs/ This is a valuable raw material for production of vaccines without any special hen keeping technologies and vaccinations against definite diseases. The article presents data on the selection efficiency in the population of Russian white chickens as a way to increase vaccine raw materials output for bioindustry. It was established that by means of selection for 2 generations of chickens the frequency of occurrence of hens with high extraembryonic liquid output of their embryos was increased by 23,4 %, the egg weight was increased by 4.7 g, and egg production over 7 months of laying by 6 eggs.

vaccine raw materials, selection, developing chicken embryos, virus titre, allantoin-amnionic fluid, weight of eggs, egg laying

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