The influence of homogeneous and heterogeneous selection on bulls considering innate immunity factors

Abstract

The syrveys have been performed with the Holstein bull sires belonging to the Head Center for Reproduction of Farm Animals, Public Corporation (Bykovo, Moscow Region). The animals are produced with the methods for selection lines (N=8) and crosses between the lines (N=21). The study of immunological indicators, including factors of cellular and humoral immunity, was conducted. The tests were performed in the laboratory of immunology "FGBNU-all-Russian research Institute of experimental veterinary medicine named after K. I. Scriabin and Ya. R. Kovalenko of the Russian Academy of Sciences". Correlations between the indicator of cellular factors of bulls- producers are studied. The result of this work revealed that in the group of bulls obtained at linear recruitment, blood lymphocytes, eosinophils were higher than in bulls, obtained by cross lines, 19.1% (P≤0.05) and by 3.76% (P≤0.05), respectively, by the factors, thereby providing the body more active protection . However, the phagocytic activity index was higher in the group of producing bulls obtained at the cross of lines by 7.7% (P≤0.05), while not reaching the standard values in both groups. In bulls obtained by heterogeneous selection, the functional activity of cellular immune factors is most stable, which is indicated by a smaller number of significant correlation coefficients (1) in this group compared to the group of bulls obtained by heterogeneous selection, in which this indicator was equal to 5: IgG / lymphocytes, neutrophils segmentonuclear/lymphocytes, neutrophils segmentonuclear/phagocytic activity, eosinophils / lymphocytes. Research results have shown that the immune system functions most evenly in breeding bulls obtained by crossing lines, which should be taken into account when obtaining breeding bulls.