Morphofunctional features of ovaries in repair pigs after stimulation with a preparation of natural sexual pheromones of a boar

Purpose: development of a new way to obtain a drug of natural genital pheromones of boar, and its approbation in production conditions.
Materials and methods. A method of manufacturing a drug of natural genital phargs, including grinding of testicles, obtained from half-arms, incubated homogenizates at a temperature of 37-39 ° C for 50-60 min, adding inkubat urine of semi-cream boars and distillation of the mixture in the rotary evaporator R-213B to the urine incubate. The finished preparation was a transparent liquid of a yellowish shade with a specific smell. Checking the drug on pigs showed its harmlessness, clinical parameters and general hematological indicators in animals after treatment with the drug were within physiological boundaries.
Results. In the scientific and production experiment, it was established that after stimulation of 5-month-old impaired repair pigs with a preparation in a dose of 0.5 ml / goal twice a day, sexual ripening has occurred at a 178-day age, which was 6 days before compared to Pilts stimulated by a synthetic analogue of the Formon Sidor (Germany's production) and 14 days earlier than in the pigs of the control group. It was found that pigs treated with the preparation made for 20 days of experiment in the blood contained more estradiol-17β (81.3 ± 4.0 pmol / l) and progesterone (37.7 ± 2.5 nmol / l) than Sidor stimulated pigs (75.7 ± 3.5 pmol / l; 31.1 ± 2.0 nmol / l) and in control animals (64.4 ±, 1 pmol / l; 28.1 ± 2.0 mol / l). The drug has a positive impact on the development of ovaries. In the pigs after stimulation in the 8-month-old age, the mass indicators, volume, linear parameters of the ovaries, as well as the number of follicles and the yellow bodies of the past sex cycle exceeded those in the control animals and pigs undergoing stimulation by Sidor.
Conclusion. Research suggests that the method developed by us allows us to obtain a natural genital cartridge pheromone preparation with high biological activity. As a natural stimulator, sex pheromones through olfactory analyzers have a stimulating effect on the relevant cerebral centers and through them to the hypothalamic-pituitary complex, which activates the growth and hormonal activity of ovaries. 

1. Fedorchuk E. G. The influence of various conditions for the maintenance of repair pigs on their growth, development and reproductive function in their cultivation: the current problems of intensifying the production of pork // E. G. Fedorchuk, G. S. Votchadna, A. N. Ivchenko - Ulyanovsk, 2007. – 340 p.

2. ENGOVATOV D.V. Methods of stimulation of sex hunting at repair pigs / D. V. Engovatov, K. N. Lobanov, S. A. Lomanov, V. F. Engovatov // Bulletin of Tambov State University. – 2011. – №16. – Vol. 2. – P. 698-700.

3. Rachkov I. G. Using the drug "Biorelin" for regulating the reproductive function in repair pigs / I. G. Rachkov, V. A. Weather, L. A. Kononova, L. M. Smirnova, etc. // Agricultural Journal. – 2019. – №4 (12). – P. 46-50.

4. Volodin V. A. Influence of physiological stimulation on the sexual function of repair pigs / V. A. Volodin // Agricultural biology. – 1987. – №6. – P. 111-116.

5. Voronskaya E. V. Influence of the probe for sexual development of repair pigs / E. V. Voronskaya // Veterinary medicine. – 1988. – №9. – P. 45-46.

6. Shipilov V.S. Basics of increasing the fertility of animals / V.S. Shipilov. – Smolensk "Delo". – 1994. – 159 p.

7. Strelletsky V. A. Reproductive quality of repair pigs with different methods of cultivation in the complexes of the complex / V. A. Strelletsky, Z. S. Streltsova. – Bryansk, 2010. – 272 p.

8. Kirkwood R. The Influence of Boarrelated Odours on Puberty Attainment in Qilts / R. Kirkwood, P. Hyqhes // Anim. Product. – 1983. – V.36. – №1. – P.131-136.

9. Zimmerman D. Influence of Boar Contact ON AQE AT PUBERTY IN QILTS / D. Zimmerman., I. Damme, D. Barnhile et al. // Nebrash Swine Rep. – 1991. – Vol. 91. – №219. – P.24-25.

10. Sokolov V. E. The influence of artificial sex phermic pheromone on the reproduction of pigs in industrial technology / V.E. Sokolov, E. P. Zinkevich, V. A. Volodin // Chemical Communication of Animals. – M.: Science, 1986. – P.403-408.

11. Kononov V. P. The use of synthetic sex podomon "SUIDOR" for stimulating the reproductive function in pigs / V. P. Kononov, A. G. Nomennaya, G. S. Vozkodnya // Chemical Communication of Animals. - M.: Science. – 1986. – P. 399-403.

12. Routing A. G. Stimulation of the reproductive function of pigs / A. G. Roma // Zootechnia. – 1991. – №11. – P. 63-66.

13. RF Patent №2623085. – 2017 The method of obtaining genital firms of male pets. Auth. Sein O. B., Sein D. O. Olenina N. V., Smooth Oh. A. and others.

14. RF Patent №2655842. – 2018 The method of obtaining a drug of natural genital pheromones of boar. Auth. Sein O. B., Sein D. O., Durakov V. A., Olenina N. V.